A study published in the Journal of the American College of Cardiology in 2009 showed found that anger and hostility were associated with Coronary Heart Disease (CHD) outcomes both in healthy and CHD populations.
The researchers recommended that besides conventional physical and pharmacological interventions psychological management focusing on anger and hostility should be considered in the prevention and treatment of coronary heart disease.
Reference
J Am Coll Cardiol. 2009 Mar 17;53(11):936-46. The association of anger and hostility with future coronary heart disease: a meta-analytic review of prospective evidence.